2D Echocardiographic Findings, NT-ProBNP Levels, and Outcomes in Dyspnoeic Patients: Results from the Pro-BNP Investigation of Dyspnoea in the Emergency Department- a Single Centre Experience

Background: Dyspnoeic in the emergency department with multiple co-morbidities is a diagnostic challenge. Approximately 15-20% of acute dyspneic Emergency Department due to ADHF (acute decompensated heart failure) are misdiagnosed. B-type peptide (BNP) and its amino-terminal fragment (NT-proBNP) accurately identify HF dyspnoeic patients. In general population dyspnoea, plasma pro-BNP concentrations increased left ventricular dilatation, hypertrophy, systolic dysfunction, or diastolic dysfunction but unaffected by pulmonary dysfunction.
 Aims Objectives: To study relation between NT & echocardiographic findings patients, In-hospital Mortality.
 Materials Methods: Source data- Patients admitted Room cardiac intensive care unit history dyspnea tertiary center south India, meeting inclusion exclusion criteria, were studied.
 Results: The predominantly constituted elderly population. most common co-morbid condition was hypertension. present uses an pro BNP level 900pg/ml as cut-off level. 78 patients positive for test. Echocardiography showed that 58% had LV 60% dysfunction. 42 EF >55%, 10 55-45%, 33 44-30% 15 < 30%. Mortality rate 6% whole However, seen only group it not statistically significant (p=0.46).
 Conclusions: correlates well worsening function; decreases, increases. Increase levels has be interpreted clinical context, substitute echocardiography assessing abnormalities